Postprandial Epigastric Fullness and Pyloric Valve Disturbance in Patients with Functional Dyspepsia - Analysis of Bowel Sounds and Electrogastrography

Yoon, Sang-hyub

The Journal of Internal Korean Medicine > Volume 28(4); 2007 > Article

Original Article

The Journal of Internal Korean Medicine 2007;28(4): 769-778.

機能性消化不良症患者의 食後心下痞滿과 pyloric valve의 機能障碍 - 장음과 위전도를 중심으로

윤상협

경희대학교 한의과대학 비계내과학 교실

Postprandial Epigastric Fullness and Pyloric Valve Disturbance in Patients with Functional Dyspepsia - Analysis of Bowel Sounds and Electrogastrography

Sang-hyub Yoon

3rd Dept. of Internal Medicine, Oriental Medicine, Kyung-Hee University

Correspondence

Sang-hyub Yoon ,Tel: 02-958-9142, Fax: 02-958-9136, Email: sandrock58@nate.com

Published online: December 30, 2007.

ABSTRACT

Background & Object :
Postprandial epigastric fullness is one of common symptoms in functional dyspepsia, but its pathophysiological mechanism has still been unknown. In this study, its association between postprandial epigastric fullness and pyloric valve disturbance was studied through analysis of bowel sounds and electrogastrography.

Methods :
Bowel sounds and electrogastrography were recorded together for fasting 15 min and postprandial 40 min. Parameters of bowel soundincluding motility index, sound to sound interval, standard deviation of sound to sound interval, sounds per minute, % of bowel sound, sound length, intensity, dominant frequency of sounds, and postprandial / fasting ratio of dominant frequency of sounds were analyzed with a specialized program. By electrogastrography, regularity of slow waves and power ratio were obtained.

Results:
Significances of bowel sounds appeared in motility index (p=0.046), dominant frequency of fasting (p=0.048), postprandial (p=0.003), and the ratio of postprandial/fasting (p=0.000); those of EGG parameters were shown in postprandial regularity of slow waves (p=0.006) and power ratio (p=0.011).

Conclusion:
Pyloric valve disturbance was a cause of postprandial epigastric fullness in patients with functional dyspepsia. Analysis of bowel sound might be useful in diagnosing its existence.

Key words: Functional dyspepsia, Pyloric valve, Bowel sounds, Electrogastrography