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The Journal of Internal Korean Medicine > Volume 34(4); 2013 > Article
The Journal of Internal Korean Medicine 2013;34(4): 478-483.
십전대보탕가감방을 투여한 간세포암종 환자에서 범혈구감소증 호전 및 간수치 상승 증례
김종민, 전형준, 조종관, 이연월, 유화승
대전대학교 둔산한방병원 동서암센터
Pancytopenia Improves with Compromised Liver Function in A Hepatocellular Carcinoma Patient Treated by Modified Sipjeondaebo-tang
Jong-min Kim, Hyung-joon Jeon, Chong-kwan Cho, Yeon-weol Lee, Hwa-seung Yoo
East-West Cancer Center, Dun-San Korean Medical Hospital of Dae-Jeon University
Correspondence  Hwa-seung Yoo ,Tel: 042-470-9132, Fax: 042-470-9006, Email: altyhs@dju.kr
  Published online: December 30, 2013.
ABSTRACT
Objectives:
To observe the therapeutic effects of an oriental herbal prescription in a hepatocellular carcinoma patient with splenomegaly and pancytopenia.

Methods :
Modified Sipjeondaebo-tang was prescribed three times a day to a hepatocellular carcinoma patient with splenomegaly and pancytopenia. Laboratory tests were carried out regularly to observe the therapeutic effects of the oriental herbal prescription for pancytopenia.

Results:
When treated with modified Sipjeondaebo-tang including Cinnamomi Cortex, the levels of white blood cells, red blood cells, hemoglobin, and hematocrit increased. However, aspartate transaminase, alanine transaminase, alkaline phosphatase, gamma-glutamic transpeptidase, total bilirubin, direct bilirubin levels also increased.

Conclusions:
Administering modified Sipjeondaebo-tang with Cinnamomi Cortex showed effect in improving pancytopenia but an increase in liver enzyme levels was also observed.
Key words: hepatocellular carcinoma, splenomegaly, pancytopenia, Sipjeondaebo-tang (shiquandafu-tang), Cinnamomi Cortex
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