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The Journal of Internal Korean Medicine 2003;24(2): 329-336. |
기능성 소화불량증 환자에 대한 반하사심탕 엑기스제의 임상효과 |
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Evaluation for Therapeutic Effectiveness of Banwhasashim-tang in Functional Dyspepsia |
Sang-Hyub Yoon, Bong-Ha Ryu, Ki-Won Ryu, Jin-Sung Kim |
Department of 3rd Internal Medicine, College of Oriental Medicine, Kyunghee University |
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Received: April 12, 2003, Accepted: June 16, 2003, Published online: June 30, 2003. |
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ABSTRACT |
Objective : We evaluated the therapeutic effect of Banwhasasimtang dry extract powder on gastrointestinal symptoms and its side effects in patients with functional dyspepsia.
Methods : Patients with functional dyspepsia, defined as discomfort in the epigastrium. A total 45 patients participated in this study. Dyspeptic symptoms ratio was obtained by patients, total point of symptom score / total 21 points x 100(%). On each of symptom after 4 weeks administration of Banwhasashim-tang was made by variation of symptom score: If symptoms score of posttreatment is lower than that of pretreatment, it is improved ; Otherwise aggravated, and if there is no change between them, unchangeable. When a full health condition of normal control is assumed 100%, relative health condition of dyspeptic patient could be calculated from full health condition - dyspeptic symptoms ratio . Therefore a whole satisfaction rate on symptom improvement was presented with variation of a relative health condition to dyspepsia between pretreatment and post.
Results: Banwhasashimtang significantly improved symptoms in patients. The significance was shown in both all seven items(p< 0.01, respectively) and 19.2% (p<0.01) of increase of a whole satisfaction rate on symptom improvement. There is no remarkable side-effect in all laboratory test, excepting 1 case of abdominal pain and another one case of recurred pain of chronic prostatitis.
Conclusion: Banwhasashimtang extract provides symptomatic relief in functional dyspepsia and is no remarkable sideeffect drug. |
Key words:
Functional dyspepsia, Banwhasashimtang |
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