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The Journal of Internal Korean Medicine > Volume 24(2); 2003 > Article
The Journal of Internal Korean Medicine 2003;24(2): 329-336.
기능성 소화불량증 환자에 대한 반하사심탕 엑기스제의 임상효과
Evaluation for Therapeutic Effectiveness of Banwhasashim-tang in Functional Dyspepsia
Sang-Hyub Yoon, Bong-Ha Ryu, Ki-Won Ryu, Jin-Sung Kim
Department of 3rd Internal Medicine, College of Oriental Medicine, Kyunghee University
Correspondence  Sang-Hyub Yoon ,Tel: 02-958-9142, Fax: 02-958-9136, Email: sandrock58@nate.com
Received: April 12, 2003,   Accepted: June 16, 2003,   Published online: June 30, 2003.
ABSTRACT
Objective :
We evaluated the therapeutic effect of Banwhasasimtang dry extract powder on gastrointestinal symptoms and its side effects in patients with functional dyspepsia.

Methods :
Patients with functional dyspepsia, defined as discomfort in the epigastrium. A total 45 patients participated in this study. Dyspeptic symptoms ratio was obtained by patients, total point of symptom score / total 21 points x 100(%). On each of symptom after 4 weeks administration of Banwhasashim-tang was made by variation of symptom score: If symptoms score of posttreatment is lower than that of pretreatment, it is improved ; Otherwise aggravated, and if there is no change between them, unchangeable. When a full health condition of normal control is assumed 100%, relative health condition of dyspeptic patient could be calculated from full health condition - dyspeptic symptoms ratio . Therefore a whole satisfaction rate on symptom improvement was presented with variation of a relative health condition to dyspepsia between pretreatment and post.

Results:
Banwhasashimtang significantly improved symptoms in patients. The significance was shown in both all seven items(p< 0.01, respectively) and 19.2% (p<0.01) of increase of a whole satisfaction rate on symptom improvement. There is no remarkable side-effect in all laboratory test, excepting 1 case of abdominal pain and another one case of recurred pain of chronic prostatitis.

Conclusion:
Banwhasashimtang extract provides symptomatic relief in functional dyspepsia and is no remarkable sideeffect drug.
Key words: Functional dyspepsia, Banwhasashimtang
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