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The Journal of Internal Korean Medicine 2003;24(3): 688-694. |
| 제 1형 신경섬유종증(NF-1) 환자에 동반된 뇌경색 1례 |
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| A Case of Cerebral Infarction Associated with Neurofibromatosis Type 1 |
| Byoung-Mu Jeong, Min-Kyung Hyun, Joong-Hwan An, Ji-Cheon Jeong, Cheol-Ho Yoon |
| Department of Internal Medicine, College of Oriental Medicine, Dongguk University |
| Correspondence |
Byoung-Mu Jeong ,Tel: 054-770-1341, Fax: 054-770-1500, Email: mania@ur21.org
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Published online: September 30, 2003. |
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| ABSTRACT |
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Neurofibromatosis(NF) is an autosomal disorder characterized by neurofibromas and cafe-au-lait spots. NF affects the various kinds of organs, and result being a variety of congenital disorder. But, it have been very rarely reported about cerebrovascular diseases associated NF. We report one case of 55-year-old male admitted to the hospital with a left-sided weakness. On physical examination, we found cafe au-lait spots and neurofibromas. Computed tomographic(CT) scan of brain showed multiple infarction areas in the territory of middle cerebral artery. He complaints the left leg s numbness and spasm onsetting every night. We apply the muscle relaxant(Baclofen) for him, but it was not effective. Then, we admitted the Korean Oriental Herbal Medicine Samgieum( Sanqi-yin), and his symptom was improved. In this case, according to the brain CT and the other cases reported in the literature, the cerebral infarction seem to be a manifestation of vasculopathy in NF-1. We discussed the pathophysiology of vascularpathy in patient with NF-1. |
| Key words:
neurofibromatosis, cerebrovascular disease, cerebral infarction |
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