| 除濕順氣湯이 高脂血症 病態 모델에 미치는 影響 |
| 김정현, 조현경, 유호룡, 설인찬, 김윤식 |
| 대전대학교 한의과대학 내과학교실 |
| The Effects of Jeseubsungi-tang on Dietary Hyperlipidemia-induced Mice |
| Jung-hyun Kim, Hyun-kyung Jo, Ho-rhyong Yoo, In-chan Seol, Yoon-sik Kim |
| Department of Internal Medicine, College of Oriental Medicine, Daejeon University, Daejon, Korea. |
| Correspondence |
Yoon-sik Kim ,Tel: 042-229-6806, Fax: 042-254-3403, Email: yoonsik@dju.ac.kr
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Received: January 27, 2006, Accepted: February 21, 2006, Published online: March 30, 2006. |
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| ABSTRACT |
Objectives:
This experiment was performed to determine the effects of the Jeseubsungi-tang(JSSGT) on hyperlipidemiainduced by hypercholesterolemic diet in mice.
Methods :
C57BL/6 mice were sensitized with a hypercholesterolemic diet for 6 weeks. Experimental group was treated with 150㎎/㎗ concentrations of JSSGT for 4 weeks (once a day).
Results:
JSSGT-treated mice showed a body weight decrease compared to normal group. JSSGT-treated mice showed a significant decrease in cholesterol, total cholesterol, triglyceride, ALT and LDL-cholesterol levels compared to hyperlipidemiainduced control group. However, HDL-cholesterol levels in JSSGT-treated group significantly increased compared to the hyperlipidemia-induced control group.
Conclusion:
These results suggest that JSSGT is effective in treating hyperlipidemia. Because only hyperlipidemic mice were studied, further research is needed. |
| Key words:
Hyperlipidemia, Jeseubsungi-tang, Cholesterol, Triglyceride |
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