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The Journal of Internal Korean Medicine 2007;28(2): 217-229. |
| 보장지사탕의 항사하작용에 관한 연구 |
| 이선령, 류봉하, 박재우 |
| 경희대학교 한의과대학 비계내과학 교실 |
| Experimental Studies on the Anti-cathartic Effects of Bojangjisa-tang |
| Seon-young Lee, Bong-ha Ryu, Jae-woo Park |
| 3rd Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Hee University |
| Correspondence |
Bong-ha Ryu ,Tel: 02-958-9137, Fax: 02-958-9136, Email: rbongh@khu.ac.kr
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Published online: June 30, 2007. |
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| ABSTRACT |
Objectives:
The aim of this experimental study was to investigate the effects of Bojangjisa-tang on anticatharsis by using mice and Guinea pigs.
Methods :
We observed the actions on gastrointestinal smooth muscles, on the transportability of small and large intestines and on diarrhea induced by castor oil, philocarpine, and barium chloride.
Results:
Bojangjisa-tang showed alleviation of the contraction of gastrointestinal smooth muscles induced by acetylcholine chloride and barium chloride. The transportability of the large intestine was constrained by Bojangjisa-tang, which also showed substantial anti-cathartic effects on diarrhea induced by castor oil, philocarpine and barium chloride.
Conclusion:
These results demonstrate that Bojangjisa-tanghas advantageous effects on drug-induced diarrhea and will contribute to the development of diarrhea treatment through further related studies. |
| Key words:
Bojangjisa-tang, Anticathartic action |
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