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The Journal of Internal Korean Medicine > Volume 22(2); 2001 > Article
The Journal of Internal Korean Medicine 2001;22(2): 251-256.
한약 투여후 발생한 급성담즙정체성(약제유인성)간염 치험 1례
양재훈, 이지연, 김관식, 정용준, 김형균, 이언정, 최우정, 한상칠, 오명진, 오로사
원광대학교 한의과대학 전주한방병원 내과
One Case Report of Acute Cholestatic-Hepatitis(Drug Induced Hepatitis) After Taking Herbal-Medicine
Jae-Hoon Yang, Ji-Youn Lee, Kwan-Sik Kim, Yong-Jun Jeong, Hyung-Kuen Kim, Eon-Jeong Lee, Woo-Jung Choi, Sang-Chil Han, Moung-Jin O, Ro-Sa O
Department of Internal Medicine, Wonkwang University of Oriental, Medicine, Chonju, Korea
Correspondence  Jae-Hoon Yang ,
Received: June 26, 2001,   Accepted: August 7, 2001,   Published online: June 30, 2001.
ABSTRACT
In western medicine, there are some reports about herbal medicine induced hepatitis, but in oriental medicine, there are few reports about that. We experienced one case of drug acute cholestatic-hepatitis in the treatment of oriental medicine for HNP. We treated the patient with acupuncture, physical therapy and herb medicine. The patient s symptoms improved after two weeks of treatment. In the course of treatment, the patient intermittently complained of general weakness, nausea, yellowish urin, dyspepsia, and abdominal discomfort. We recognized that total bilirubin(7.2mg/dl), direct bilirubin(5.5mg/dl), serum transaminase(AST 360U/L, ALT 354U/L), alkaline phosphatase(16.6 K/A), urobilinogen(++) and bilirubin(++) were elevated. We diagnosed drug induced hepatitis. We stopped giving herb medicine and began giving Saeng gan gunbi-tang and Injin-oryung-san. Saeng gan gunbi-tang and Injin-oryung-san have been used to treat hepatic disease and have been known to have beneficial effects. After 3weeks on medication, the clinical symptoms and liver function improved. So, we report this case to bring more attention to the safety and toxicity of herbal medicine.
Key words: drug induced hepatitis, herbal medicine
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