| 당귀추출물 전처치가 Rat 의 혈중알코올 및 알데히드 농도에 미치는 영향 |
| 정우상, 송재철, 박정미, 김상우 |
| 포천중문의대 분당차병원 임상의학위원회 |
| The Effect of the Extract of Angelica gigas on the Serum Alcohol and Acetaldehyde Concentration in Rats |
| Woo Sang Jung, Jae Chul Song, Jung Mi Park, Sang Woo Kim |
| Institutional Research Board, Pochon CHA University |
| Correspondence |
Woo Sang Jung ,Tel: 031-780-6101, Fax: 031-780-6120, Email: WSJung@cha.ac.kr
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Received: June 4, 2002, Accepted: July 31, 2002, Published online: June 30, 2002. |
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| ABSTRACT |
Objectives:
Our study was designed to assess whether the extract of Angelica gigas can lower serum alcohol and acetaldehyde concentration in drunken rats.
Methods :
We divided Sprague-Dawley male rats into 3 groups of a Vehicle control, Positive control and Angelica gigas group. Serum alcohol and acetaldehyde levels were checked at baseline, 0.5, 1, 2 and 4 hours after drinking ethanol. Independent t-test was performed to assess the difference of the serum concentrations between the Angelica gigas induced group and the control group.
Results:
Angelica gigas lowered the serum acetaldehyde concentration. However, it did not lower alcohol concentration effect.
Conclusions:
We assume that Angelica gigas could be effective for alcohol-induced hangover. |
| Key words:
Angelica gigas, Alcohol, Acetaldehyde, Hangover. |
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